… The diagram on the right depicts how an inhibitory GATA-2 C-finger … in which GATA-2–dependent
pathogenesis is independent of … In contrast, GATA-2 N-terminal zinc finger (N-finger) …

… of two highly conserved domains, the N-terminal (N-ZnF) and … that functions of SrpNC that
are independent of Ush, are … stability of DNA binding on more complex binding sites. However, …

… mutants interact with the DNA, independent of the presence of the second GATA-type zinc-…
N-terminal zinc-finger is shown to recognize the AGAT[C/G/T] motif and directs DNA binding in …

… (plus one adjacent residue on the N-terminal side) of three … one flanking residue on the
N-terminal side) of various GATA … the double zinc finger DNA-binding domain regardless of the …

… fingers, which are referred to as the N-terminal zinc finger (N-… partners but can also bind
to DNA independently with a slightly … DNA binding domain (Figure 1C) containing both zinc …

… Since its discovery 40 years ago in chicken cells, the family of … recruitment occurs independently
of GATA sites. Strikingly, … Like Dal80, GATA-1 and GATA-2 only occupy a small subset …

… point mutations within the N-terminal zinc finger motif of GATA1. … acids and makes
sequence-specific contacts with DNA. A … PD can either bind DNA independently or as a …

… domain, and variable N-terminal domain and binds an octamer … independently with DNA as
well as transactivation domains … enabling binding to DNA in a sequence-specific manner (99–…

… We then performed knockdown of COP1 using three independent … N-terminal 270 amino
acid [270 aa] of GATA2), the NCF fragment (containing both the N- and C-terminal zinc fingers), …

… Histone PTMs are mostly found on the N-terminal of the … expressed, whereas GATA-2 and
GATA-3 are transcribed at … looked at transcription and replication independent variant H3.3 …